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Low-Calorie, Fasting-Mimicking Diet May Benefit Those With Crohn's Disease

Rubenhair Latvia
2 min read
29.12.2025
Low-Calorie, Fasting-Mimicking Diet May Benefit Those With Crohn's Disease

a rephrased version of the article for a clinic website: A groundbreaking study published in Nature Medicine has revealed that a fasting-mimicking diet may be beneficial for individuals living with Crohn’s disease.

a rephrased version of the article for a clinic website:

A groundbreaking study published in Nature Medicine has revealed that a fasting-mimicking diet may be beneficial for individuals living with Crohn’s disease.

Improving Symptoms and Biological Indicators

Researchers from Stanford found that a short-term calorie-restricted diet, involving five consecutive days of reduced caloric intake per month for three months, led to significant improvements in symptoms and biological indicators of the disease. The study involved 97 participants with mild to moderate Crohn’s disease.

Fasting-Mimicking Diet: A Promising Approach

Participants who followed the fasting-mimicking diet experienced a reduction in gut inflammation, as evidenced by lower levels of calprotectin protein in their stool and reduced production of inflammatory molecules by immune cells. These findings suggest that this approach may be an effective way to manage Crohn’s disease symptoms.

Expert Insights

"We were very pleasantly surprised by the results," said Sidhartha R. Sinha, MD, senior author on the paper and assistant professor of gastroenterology and hepatology at Stanford. "This study provides valuable evidence for physicians to recommend dietary interventions to their patients."

Important Considerations

While the study suggests that a fasting-mimicking diet may be beneficial for some individuals with Crohn’s disease, it's essential to note that this approach may not be suitable for everyone. Patients should consult with their healthcare provider before starting any new dietary regimen.

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