Hair News

Stopping GLP-1s May Lead to Weight Regain In Less Than 2 Years, Review Finds

Rubenhair Latvia
2 min read
12.01.2026
Stopping GLP-1s May Lead to Weight Regain In Less Than 2 Years, Review Finds

**Understanding Weight Regain After GLP-1 Medications** Are you considering using GLP-1 medications, such as semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound), to help with weight loss and improve your overall health?

**Understanding Weight Regain After GLP-1 Medications**

Are you considering using GLP-1 medications, such as semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound), to help with weight loss and improve your overall health? While these medications have been shown to be effective in promoting significant weight loss, it's essential to understand what happens when you stop taking them.

Research has found that people who discontinue GLP-1 medications tend to regain their lost weight within a relatively short period. In fact, studies suggest that the average person regains all of their weight within 2 years of stopping treatment. This is concerning, as it indicates that these medications may not lead to long-term weight loss on their own.

However, experts agree that there are ways to minimize weight regain and achieve lasting results. One approach is to gradually taper off the medication rather than quitting abruptly. Additionally, incorporating supportive changes in diet, exercise, and lifestyle can help maintain weight loss over time.

**The Importance of a Comprehensive Approach**

A recent review published in The BMJ highlights the need for a more comprehensive approach to achieving lasting weight loss with GLP-1 medications. The researchers suggest that simply relying on medication may not be enough to achieve long-term results, and that a combination of behavioral changes and lifestyle modifications is necessary.

**Assessing Weight Management After GLP-1s**

To better understand the effects of GLP-1 medications on weight loss, a team of researchers conducted a comprehensive review of existing studies. They analyzed data from 37 studies involving over 9,000 adults with overweight or obesity and found that:

  • People lost an average of 18 pounds while taking medication.
  • However, once they stopped treatment, they regained their lost weight at a rate of about 1 pound per month.
  • Within an average of 1.7 years, most participants had regained all of their weight.

The researchers also noted that newer GLP-1 medications, such as semaglutide and tirzepatide, were associated with a faster rate of regain.

**Takeaways**

While GLP-1 medications can be effective in promoting significant weight loss, it's essential to understand the potential risks of weight regain after stopping treatment. By incorporating supportive changes in diet, exercise, and lifestyle, you can minimize weight regain and achieve lasting results. Consult with our healthcare professionals to determine if a comprehensive approach is right for you.

Learn more about hair transplant at Rubenhair clinic.

Get a Free Consultation

Consult with our specialists about FUE procedure, PRP therapy or hair transplant.

Do you have questions?

Contact us and get a free consultation about hair transplantation

+371 267 777 76